Figure 4
CAS regulates MMP-2 translocation. (a) Double-stain immunofluorescence analyses of MMP-2 and CAS distributions in MCF-EV, MCF-CAS, and MCF-anti-CAS cells. Please note the increased distribution of MMP-2 in the cell protrusions of MCF-CAS cells. Arrows indicate some of the cell protrusions. The scale bar represents 20 μm. (b) Double-stain immunofluorescence showed CAS was colocalized with cytoplasmic vesicle and MMP-2 in MCF-CAS cells. Arrows indicate some of the colocalizations. The scale bar represents 30 μm.