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Figure 5 | Journal of Experimental & Clinical Cancer Research

Figure 5

From: CSE1L/CAS, the cellular apoptosis susceptibility protein, enhances invasion and metastasis but not proliferation of cancer cells

Figure 5

CAS regulates MMP-2 secretion and invasion of cancer cells. (a) CAS regulates MMP-2 secretion of MCF-7 cells. (b) Matrigel-based invasion assays of MCF-EV, MCF-CAS, and MCF-anti-CAS cells. Data represent the means of three independent experiments. (c) Immunoblotting of CAS expression in B16-EV, B16-CAS, and B16-anti-CAS cells. (d) CAS regulates MMP-2 secretion of B16-F10 cells. (e) Matrigel-based invasion assays of B16-CAS, B16-EV, and B16-anti-CAS cells. The upper is a representative photograph of the invaded cells. Data represent the means of three independent experiments.

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