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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat

Figure 1

Morphological observations of classic ACF, dark ACF and tumors. Morphological observations of classic ACF, dark ACF and tumors. Lesions were stained with methylene blue and examined with the stereomicroscope (A, D, ×20); black arrowheads represent classic ACF and white arrowheads represent dark ACF. Histological observation (B, C, E) are derived from the same lesions as seen in A and D. Classic ACF showed hyperplasia without dysplasia (B, ×100); dark ACF showed moderate dysplasia (C, ×100); small tumor showed severe dysplasia (E, ×100).

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