From: Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat
crypt multiplicity (No. of crypts/lesion/group)
W8-14
W16-21
W22-25
F
P
Classic ACF
3.93 ± 0.89
4.73 ± 1.12
4.52 ± 1.03
3.17
0.278
Dark ACF
6.00 ± 3.00
10.73 ± 4.03
18.38 ± 3.54
15.40
0.000
t
3.330
9.883
11.204
0.002