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Figure 6 | Journal of Experimental & Clinical Cancer Research

Figure 6

From: Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145

Figure 6

Changes in mRNA levels of apoptosis related genes in DU-145 cells exposed to docetaxel and ATRA combination as compared to untreated controls. mRNA profiles of apoptosis related genes were obtained by using Oligo GEArray Human Apoptosis (SuperArray, Frederick, MD, USA). mRNAs were isolated from untreated, docetaxel treated, ATRA treated and combination of docetaxel and ATRA treated DU-145 cells. Survivin (BIRC5), MLC-1 and LTβR mRNA levels were significantly downregulated by combination treatment. P < 0,05 was considered significant.

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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