From: Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145
Concentration of drugs
CI value
DOC (0,01 nM) + ATRA (60 μM)
0.254
Strong synergism
DOC (0,1 nM) + ATRA (80 μM)
0.300
DOC (0,1 nM) + ATRA (60 μM)
0.219