Figure 1From: Efficient inhibition of murine breast cancer growth and metastasis by gene transferred mouse survivin Thr34→Ala mutantFluorescence microscopic appearance of propidium iodide (PI)-stained nuclei. 4T1 cells were treated with Msurvivin T34A plasmid(2 μg per well)for 48 hr. (a) untransfected (b)transfected with PORF-9 null plasmid(c)transfected with Msurvivin T34A plasmid, reduction of cell volume, condensation of nuclear, nuclear fragmentation, and apoptotic bodies.Back to article page