Figure 5From: Efficient inhibition of murine breast cancer growth and metastasis by gene transferred mouse survivin Thr34→Ala mutantInhibition of intratumoral angiogenesis assayed by CD31 staining of microvessel. Vascularization within tumors was detected by an antibody to CD 31 and vascular density was quantified by counting the number of microvessel per high power field (×400). (A) Shown are representative sections from each group. (a)NS group, (b) PORF-9 null plasmid group, (c) Msurvivin T34A plasmid group. The arrows point to the necrosis. (b) CD31 positive microvessel in each group. Values were expressed as means ± SE (5 high power fields/slide).Back to article page