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Table 2 Genotype distribution in colorectal cancer and Allele frequency

From: Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population

          Allele frequency
Genotype patients (n = 68) controls (n = 121) crude adjusted   patients controls
  n % n % OR (95%CI) p OR (95%CI)a p   % %
OGG1            
   Ser/Ser 17 25.0 39 32.2 1.00   1.00   Ser 52.9 54.6
   Ser/Cys,Cys/Cys 51 75.0 82 67.8 1.43 (0.73–2.78) 0.297 1.43 (0.69–2.95) 0.332 Cys 47.1 45.5
MUTYH            
   Gln/Gln 8 11.8 37 30.6 1.00   1.00   Gln 39.0 59.1
   Gln/His,His/His 60 88.2 84 69.4 3.30 (1.44–7.60) 0.005 3.53 (1.44–8.70) 0.006 His 61.0 40.9
APEX1            
   Asp/Asp 23 33.8 70 57.9 1.00   1.00   Asp 64.0 74.8
   Asp/Glu,Glu/Glu 45 66.2 51 42.1 2.69 (1.45–4.99) 0.002 2.33 (1.21–4.48) 0.011 Glu 36.0 25.2
XRCC1            
   Arg/Arg 42 61.8 62 51.2 1.00   1.00   Arg 78.7 71.1
   Arg/Gln,Gln/Gln 26 38.2 59 48.8 0.65 (0.36–1.19) 0.164 0.60 (0.31–1.15) 0.125 Gln 21.3 28.9
  1. a: OR adjusted for gender, age, smoking habit