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Table 3 Genotype distribution in relation to subsites in colorectal cancer

From: Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population

Genotype Colon cancer Rectal cancer
  patients (n = 40) controls (n = 121) crude adjusted patients (n = 23) controls (n = 121) crude adjusted
  n % n % OR (95%CI) p OR (95%CI)a P n % n % OR (95%CI) p OR (95%CI)a p
OGG1                 
   Ser/Ser 10 25.0 39 32.2 1.00   1.00   5 21.7 39 32.2 1.00   1.00  
   Ser/Cys,Cys/Cys 30 75.0 82 67.8 1.43 (0.63–3.21) 0.390 1.28 (0.55–2.99) 0.567 18 78.3 82 67.8 1.71 (0.59–4.95) 0.321 1.66 (0.56–4.87) 0.359
MUTYH                 
   Gln/Gln 4 10.0 37 30.6 1.00   1.00   3 13.0 37 30.6 1.00   1.00  
   Gln/His,His/His 36 90.0 84 69.4 3.96 (1.32–11.95) 0.014 3.95 (1.28–12.20) 0.017 20 87.0 84 69.4 2.94 (0.82–10.49) 0.097 3.06 (0.84–11.11) 0.089
APEX1                 
   Asp/Asp 12 30.0 70 57.9 1.00   1.00   11 47.8 70 579 1.00   1.00  
   Asp/Glu,Glu/Glu 28 70.0 51 42.1 3.20 (1.49–6.89) 0.003 3.04 (1.38–6.71) 0.006 12 52.2 51 42.1 1.50 (0.61–3.66) 0.376 1.61 (0.64–4.09) 0.315
XRCC1                 
   Arg/Arg 25 62.5 62 51.2 1.00   1.00   14 60.9 62 51.2 1.00   1.00  
   Arg/Gln,Gln/Gln 15 37.5 59 48.8 0.63 (0.30–1.31) 0.217 0.60 (0.28–1.30) 0194 9 39.1 59 48.8 0.68 (0.27–1.68) 0.398 0.62 (0.24–1.58) 0.315
  1. a: OR adjusted for gender, age, smoking habit