Effects of si-CD147 RNA on SMMC-7721 cells' invasive abilities. The invasive abilities of SMMC-7721 cells transfected with negative control and si-CD147 RNA were examined by chamber assay. HE staining and quantitative analysis were employed to analyze the number of the transmembrane cells. Transmembrane cells number dramatically reduced in SMMC-7721 cells transfected with si-CD147 (A). The graph (B) compares the number of transmembrane cells and indicates an 85% inhibition by si-CD147. ***P < 0.001 v.s. control.