| |
P value on CSS
|
P value on RFS
|
|---|
|
Variables
|
Univariatea
|
Multivariateb
|
Univariatea
|
Multivariateb
|
|---|
|
Age
|
0.556
|
0.236
|
0.522
|
0.413
|
|
Gender
|
0.598
|
0.326
|
0.885
|
0.590
|
|
TNM stage
|
<0.001
|
<0.001
|
<0.001
|
<0.001
|
|
Tumor size
|
<0.001
|
<0.001
|
<0.001
|
<0.001
|
|
Grade
|
0.388
|
0.078
|
0.085
|
0.219
|
|
Histology
|
0.859
|
0.396
|
0.704
|
0.730
|
|
ECOG-PS
|
0.046
|
0.874
|
0.259
|
0.427
|
|
Necrosis
|
<0.001
|
0.117
|
<0.001
|
0.242
|
|
p27Kip1
|
<0.001
|
0.003
|
<0.001
|
0.002
|
|
Skp2
|
<0.001
|
0.360
|
0.001
|
0.966
|
|
Cks1
|
0.002
|
0.110
|
0.029
|
0.482
|
- Note: OS: overall survival; CSS: cancer-specific survival; RFS: recurrence-free survival.
- a Statistical analyses were performed by the log-rank test.
- b Statistical analyses were performed by Cox proportional-hazards regression model.
