Figure 8From: Antisense inhibition of ATM gene enhances the radiosensitivity of head and neck squamous cell carcinoma in miceThe apoptosis of SCCVII cells in vivo after irradiation. (A) Apoptotic cells are detected by TUNEL. The nuclei of apoptotic cells were stained brown as observed under light microscopy (magnification, × 400). (B) The treatment by irradiation in combination with ATM AS-ODNs injection enhanced the apoptotic rate of tumor cells. * P < 0.05, there was a significant difference in the AI of tumors treated with irradiation alone compared with the untreated group and the group treated with ATM AS-ODNs alone. ** P < 0.05, compared with the other groups.Back to article page