Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer

Table 3 The average number of nerves near and far from the tumor tissue in the three groups

Groups	CXCL12-treated group (n = 8)	Untreated control group (n = 10)	AMD3100-treated group (n = 10)
Number of nerves near tumor	8.73 ± 4.42*#	5.11 ± 2.39*	2.80 ± 1.19#
Number of nerves far from tumor	1.91 ± 1.10	2.22 ± 1.64	1.24 ± 0.66
F value	9.49

# The differences of the number of nerves between the CXCL12-treated group and the control group and between the AMD3100-treated group and the control group are statistically significant. (P < 0.05).* The differences between the number of nerves near the tumor and the number of nerves far from the tumor in CXCL12-treated group and untreated control group are statistically significant (P < 0.05).

ISSN: 1756-9966