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Table 2 Association between Id-1, EGFR, VEGF, tumour grade and Dukes' stage.

From: Id-1: Regulator of EGFR and VEGF and potential target for colorectal cancer therapy

  Grade Dukes' Stage
  G1(n = 10) G2 (n = 21) G3 (n = 15) A+B (n = 19) C+D (n = 27)
Id-1      
   Absent 2 (20%) 1 (4.8%) 0 (0%) 3 (15.8%) 0 (0%)
   Weak 3 (30%) 9 (42.8%) 1 (6.7%) 2 (10.6%) 3 (11.1%)
   Moderate 5 (50%) 8 (38.1%) 5 (33.3%) 6 (31.5%) 10 (37%)
   Strong 0 (0%) 3 (14.3%) 9 (60%) 8 (42.1%) 14 (51.9%)
   p-value p = 0.005 (G1 versus G2) p = 0.0012 (G2 versus G3) p = 0.018
EGFR      
   Absent 3 (30%) 2 (9.5%) 0 (0%) 5 (26.4%) 0 (0%)
   Weak 3 (30%) 8 (38.1%) 2 (13.3%) 3 (15.8%) 5 (18.6%)
   Moderate 3 (30%) 7 (33.3%) 3 (20%) 4 (21%) 9 (33.3%)
   Strong 1 (10%) 4 (19.1%) 10 (66.7%) 7 (36.8%) 3 (48.1%)
   p-value p = 0.002 (G1 versus G2) p = 0.001 (G2 versus G3) p = 0.03
VEGF      
   Absent 3 (30%) 1 (4.7%) 0 (0%) 4 (21%) 0 (0%)
   Weak 2 (20%) 7 (33.3%) 1 (6.7%) 3 (15.8%) 5 (18.6%)
   Moderate 2 (20%) 8 (38.1%) 3 (20%) 5 (26.4%) 10 (37%)
   Strong 3 (30%) 5 (23.9%) 11 (73.3%) 7 (36.8%) 12 (44.4%)
   p-value p = 0.05 (G1 versus G2) p = 0.04 (G2 versus G3) p = 0.04