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Table 1 Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis (RPA) groups in patients with locally-advanced non-small-cell lung cancer (LA-NSCLC).

From: Prophylactic cranial irradiation in locally advanced non-small cell lung cancer: outcome of recursive partitioning analysis group 1 patients

RPA Group Definition Median survival (months)
I KPS of > or = 90, who received chemotherapy 16.2
II KPS of > or = 90, who received no CT, but had no PE 11.9
III KPS < 90, younger than 70 years, with non-large cell histology 9.6
IV KPS > or = 90, but with PE, or KPS < 90, younger than 70 years, and with large cell histology, or older than 70 years, but without PE 5.6–6.4
V older than 70, with PE 2.9
  1. Abbreviations: KPS: Karnofsky Performance Status; CT: Chemotherapy; PE: Pleural effusion.