Skip to main content

Table 2 No caption

From: TRAIL and Taurolidine induce apoptosis and decrease proliferation in human fibrosarcoma

a: Summary of the selected candidate genes' microarray data (/stands for no value).
Microarray Probeset 201167_x_at 201168_x_at 210538_s_at 202014_at 203725_at 200799_at 200800_s_at 202581_at 214786_at 205192_at 201502_s_at
Gene Symbol
SLR = log2(RQ)
ARHGDIA ARHGDIA///LOC728908 BIRC3 PPP1R15A/Gadd34 GADD45A HSPA1A HSPA1A///HSPA1B HSPA1B MAP3K1 MAP3K14 NFKBIA
Ta+TR vs Ko_SLR -0,74 / -1,45 1,55 1,46 2,54 3,28 2,45 -0,04 / 2,47
TR50 vs Ko_SLR 1,19 0,43 / / / / / / / / 1,17
Ta250 vs Ko_SLR -0,55 -0,28 / 0,95 1,33 2,49 2,99 2,06 / -1,35 2,03
Ta+TR vs TR50_SLR -1,95   -2,32 1,22 1,55 2,61 2,96 2,44 -1,32 -1,34 1,3
Ta+TR vs Ta250_SLR / 0,49 / 0,61 / / 0,25 0,43 / / 0,45
b: Summary of the selected candidate genes' rtPCR data. The correlation with the findings of the microarray is high except for ARGHGDIA.
Taqman assay Hs00976924_g1 Hs00154109_m1 Hs00169585_m1 Hs00169255_m1 Hs00359163_s1 Hs01040501_+sH Hs01089753 Hs00394890_m1 Hs00153283_m1   
Gene Symbol
SLR = log2(RQ)
ARGHGDIA BIRC3 GADD34 GADD45A HSPA1A HSPA1B MAP3K14 MAP3K1 NFKBIA   
TA+Tr vs Control -0,4205 -1,1638 1,2819 2,4504 3,8893 3,1561 -0,8706 -0,5410 2,3151   
TR50 vs Control -0,1207 1,1527 0,2107 0,7523 0,4395 0,4545 0,1833 0,0203 1,5287   
TA25 vs Control 0,0120 -0,3926 1,4327 2,8888 3,6653 3,5939 -0,7547 -0,1194 2,5517   
TA+Tr vs TR50 -0,2998 -2,3165 1,0712 1,6981 3,4498 2,7016 -1,0539 -0,5613 0,7864   
TA+Tr vs TA25 -0,4325 -0,7712 -0,1508 -0,4385 0,2240 -0,4378 -0,1159 -0,4217 -0,2366