Figure 4
From: PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway
The cell cycle distribution of K562 cells transfected with Ad-PTEN-GFP or Ad-GFP and treated with or without 10 nM RAPA detected by flow cytometry. A: transfected with Ad-GFP; B: transfected with Ad-GFP and treated with 10 nmol/L RAPA; C: transfected with Ad-PTEN-GFP; D: transfected with Ad- PTEN-GFP and treated with 10 nmol/L RAPA. After treated with 10 nmol/L RAPA for three days, the apoptosis rate of K562 cells was 31.5% in Ad-PTEN-GFP group, which significantly higher than that of 6.8% in Ad-GFP group_P < 0.01).