Figure 4
From: Mutation analysis of Rad18 in human cancer cell lines and non small cell lung cancer tissues
In vitro study of Rad18 WT and Rad18 SNP. A: Expression of introduced Rad18 assessed by RT-PCR (top) and Western blotting (bottom). Lane 1: PC3 + LacZ, 2: PC3-WT Rad18, 3: PC3-SNP Rad18. B: Cell morphology of the three cell lines. C: Growth assay of the three cell lines. D: Sensitivity to CDDP (left) and CPT-11 (right) in the three cell lines. E: Percent survival at day 7 for different dose of CDDP (left) and CPT-11 (right).