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Table 3 Main results of the pooled data in the meta-analysis

From: Polymorphisms of TP53 codon 72 with breast carcinoma risk: evidence from 12226 cases and 10782 controls

  No. of cases/controls Arg/Arg vs Pro/Pro (Arg/Arg+Arg/Pro) vs Pro/Pro Arg/Arg vs (Arg/Pro+Pro/Pro)
   OR (95%CI) P P (Q-test) OR (95%CI) P P (Q-test) OR (95%CI) P P (Q-test)
Random-effect model
Total 12226/10782 1.20 (0.96–1.50) 0.11 0.000 1.12 (0.96–1.32) 0.14 0.01 1.13 (0.98–1.31) 0.10 0.000
Caucasian 11549/9830 1.15 (0.91–1.44) 0.24 0.001 1.11 (0.95–1.30) 0.17 0.06 1.09 (0.93–1.27) 0.28 0.000
Asian 631/873 1.36 (0.61–3.03) 0.45 0.000 1.19 (0.67–2.10) 0.55 0.006 1.22 (0.72–2.05) 0.46 0.002
African 46/79 1.46 (0.38–5.62) 0.58 0.76 1.12 (0.31–4.10) 0.86 0.45 1.60 (0.63–4.06) 0.32 0.22
Fixed-effect model
Total 12226/10782 1.09 (0.99–1.20) 0.10 0.000 1.09 (0.99–1.19) 0.06 0.01 1.04 (0.99–1.10) 0.13 0.000
Caucasian 11549/9830 1.07 (0.96–1.18) 0.24 0.001 1.08 (0.98–1.19) 0.12 0.06 1.03 (0.98–1.09) 0.25 0.000
Asian 631/873 1.27 (0.94–1.71) 0.12 0.000 1.16 (0.89–1.51) 0.26 0.006 1.15 (0.92–1.44) 0.22 0.002
African 46/79 1.47 (0.39–5.62) 0.57 0.76 1.17 (0.33–4.14) 0.80 0.45 1.67 (0.80–3.48) 0.17 0.22