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Table 2 Prognostic factors for overall survival

From: Impact of relative dose intensity (RDI) in CHOP combined with rituximab (R-CHOP) on survival in diffuse large B-cell lymphoma

 

Univariate model

Multivariate model

Factor

HR (95%CI)

P value

HR (95%CI)

P value

Age (61 ≤)

2.2 (0.8–6.7)

0.15

-

-

Sex (male)

2.6 (0.7–9.3)

0.14

-

-

Stage III, IV

7.6 (1.0–5.8)

0.15

-

-

Extranodal site (2 ≤)

1.7 (0.6–4.8)

0.35

-

-

LDH (> upper normal limit)

1.8 (0.5–5.8)

0.34

-

-

Performance status (2–4)

2.8 (1.0–8.1)

0.05

-

-

RDI (CPA+DOX) per 0.1

0.7 (0.6–0.9)

0.02*

0.8 (0.6–1.0)

0.08

IPI (high/high intermediate)

4.7 (1.3–17)

0.02*

3.8 (1.0–14)

0.05

Albumin (3.5 mg/dl ≤)

0.7 (0.4–1.2)

0.20

-

-

Prophylactic G-CSF

1.6 (0.5–4.9)

0.44

-

-

  1. HR: hazard ratio; CI: confidence interval; RDI: relative dose intensity; CPA: cyclophosphamide; DOX: doxorubicin; G-CSF: granulocyte colony-stimulating factor