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Table 3 Factors influencing RDI (above the Median): Univariate and Multivariate analysis

From: Impact of relative dose intensity (RDI) in CHOP combined with rituximab (R-CHOP) on survival in diffuse large B-cell lymphoma

 

Univariate model

Multivariate model 1

Multivariate model 2

Factor

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

Age (61 ≤)

0.3(0.2–0.8)

0.0099*

0.4 (0.2–0.8)

0.06

0.4 (0.2–0.8)

0.02*

Sex (male)

1.3 (0.6–2.9)

0.54

-

-

-

-

Stage III, IV

0.8 (0.4–1.9)

0.68

-

-

-

-

Extranodal site (2 ≤)

1.0 (0.4–2.3)

1.00

-

-

-

-

LDH (> upper normal limit)

0.5 (0.2–1.2)

0.11

-

-

0.6 (0.3–1.4)

0.24

Performance status (2–4)

0.6 (0.2–1.5)

0.24

-

-

-

-

IPI (high/high intermediate)

0.4 (0.2–1.0)

0.04*

0.6 (0.3–1.6)

0.33

-

-

Alb (3.5 mg/dl >)

0.8 (0.5–1.4)

0.50

-

-

-

-

Prophylactic G-CSF +

1.7 (0.7–3.8)

0.22

-

-

-

-

  1. IPI: international prognostic index. G-CSF: granulocyte colony-stimulating factor