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Figure 3 | Journal of Experimental & Clinical Cancer Research

Figure 3

From: Effect of Genistein on vasculogenic mimicry formation by human uveal melanoma cells

Figure 3

The effect of Genistein on the vasculogenic mimicry of human uveal melanoma C918 cells on 3-D collagen I cultures. PAS-stained images of C918 cells cultured on three-dimensional collagen I for 48 h in medium with different concentrations of Genistein. (A) control; (B) 25 μM Genistein; (C) 50 μM Genistein; (D) 100 μM Genistein; (E) 200 μM Genistein. At treatment groups with 25 μM and 50 μM concentrations of Genistein, C918 cells formed fewer VM matrix-association channels than do control. However, the groups treated with higher concentrations of Genistein (100 and 200 μM) did not form the VM channels. (Magnification: × 200)

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