From: MMP7 expression regulated by endocrine therapy in ERβ-positive colon cancer cells
Group | G1 (%) | G2/M (%) | S (%) | |
---|---|---|---|---|
Control | 82.2 ± 5.4 | 2.2 ± 0.5 | 15.5 ± 1.8 | |
TAM (M) | 10-7 | 75.9 ± 5.7 | 9.1 ± 2.1 | 15 ± 2.5 |
10-6 | 75.8 ± 4.5 | 9.2 ± 1.9 | 15 ± 2.1 | |
10-5 | 63.2 ± 5.1 | 7.3 ± 1.4 | 29.5 ± 3.4 | |
10-4 | 30 ± 5.6 | 2.4 ± 0.6 | 67.6 ± 4.5 | |
5-FU (μM) | 6.25 | 66.7 ± 5.4 | 0 | 33.3 ± 3.8 |
12.5 | 71.1 ± 6.2 | 0 | 28.9 ± 4.2 | |
25 | 73.7 ± 7.4 | 0 | 26.3 ± 3.2 | |
50 | 79.8 ± 7.7 | 0 | 20.2 ± 3.1 | |
12.5 μM 5-FU +TAM (M) | 10-7 | 75.0 ± 8.1 | 0 | 25.0 ± 4.2 |
10-6 | 67.8 ± 6.3 | 0 | 32.2 ± 3.1 | |
10-5 | 51.8 ± 5.5 | 0 | 48.2 ± 4.7 |