Chromophobe renal cell cancer - review of the literature and potential methods of treating metastatic disease

Table 2 Targets for Imatinib, Dasatinib and Nilotinib

Target spectrum	Imatinib	Dasatinib	Nilotinib
BCR-ABL	+	+	+
PDGFR	+	+	+
c-KIT	+	+	+
Src family kinases	-	+	-
Ephrin receptor kinases	-	+	only EphB4
NQO2	+	-	+
DDR1	+	+	+
CSF-1R	-	-	+

ISSN: 1756-9966