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Table 2 Targets for Imatinib, Dasatinib and Nilotinib

From: Chromophobe renal cell cancer - review of the literature and potential methods of treating metastatic disease

Target spectrum Imatinib Dasatinib Nilotinib
BCR-ABL + + +
PDGFR + + +
c-KIT + + +
Src family kinases - + -
Ephrin receptor kinases - + only EphB4
NQO2 + - +
DDR1 + + +
CSF-1R - - +
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