Figure 1
Photomicrographs of Epstein-Barr virus (EBV) expression in gastric cancer. Epstein-Barr virus (EBV)-encoded RNA 1 (EBER1) in situ hybridization in a gastric carcinoma reveals specific EBER1 transcripts (dark) in the nuclei of the tumor cells. 1A-B: intestinal type of gastric cancer with EBV nuclear expression. Note, all tumor glands were positive for EBV, while stromal cells between the tumor glands were negative. 1C-D: diffuse type of gastric cancer with EBV nuclear expression, while scattered lymphocytes were negative. (Original magnification × 10 in Fig. 1A&C, original magnification × 40 in Fig. 1 B&D)