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Table 2 The expression of P-gp, MRP and LRP in patients with gastric cancer of different pathological types

From: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer

   Positive rates of MDR proteinsb
Pathological typesa Numbers P-gp*
n (%)
LRP**
n(%)
MRP***
n(%)
Poorly differentiated adenocarcinoma# 18 16 (88.9) 17 (94.4) 6 (33.3)
Moderately differentiated adenocarcinoma## 23 18 (78.3) 18 (78.3) 3 (13.0)
Well differentiated adenocarcinoma ### 8 7 (87.5) 7 (87.5) 4 (50.0)
Mucous adenocarcinoma 6 6 (100) 5 (83.3) 2 (33.3)
Others c 4 4 (100) 3 (75.0) 1 (25.0)
  1. a Comparison between the expression of P-gp and LRP in the same pathological types:
  2. #:P = 0.716; r = 0.376
  3. ##:P = 0.915; r = 0.913
  4. ###:P = 0.686; r = 0.414
  5. bComparison among different pathological types for the same protein:
  6. *P = 0.561
  7. **P = 0.297
  8. ***P = 0.661
  9. cOthers included well differentiated squamous carcinoma one case, unknown pathological types 3 cases.
  10. Pearson Chis-square test and Gamma test