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Table 3 The relationship between clinico-pathological stages of gastric cancer and P-gp, MRP and LRP

From: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer

  

Positive rates of MDR proteins

Stages

Numbers

n(%)

P-gp*

n(%)

MRP

n(%)

LRP

n(%)

TNM stages

    

T2

13 (22.0)

12 (92.3)

6 (46.2)

10 (76.9)

T3

44 (74.6)

37 (84.1)

10 (22.7)

39 (88.6)

T4

2 (3.4)

2 (100)

0 (0.0)

1 (50.0)

N0

24 (40.7)

21 (87.5)

10 (41.7)

21 (87.5)

N1

18 (30.5)

14 (77.8)

2 (11.1)

15 (83.3)

N2

15 (25.4)

14 (93.3)

3 (20.0)

12 (80.0)

N3

2 (3.4)

2 (100)

1 (50.0)

2 (100.0)

M0

57 (96.6)

49 (86.0)

16 (28.1)

49 (86.0)

M1

2 (3.4)

2 (100.0)

0 (0.0)

1 (50.0)

Clinical stages

    

IB

10 (16.9)

10 (100)

6 (60.0)

9 (90.0)

II

13 (22.0)

10 (76.9)

4 (30.8)

11 (84.6)

IIIA

18 (30.5)

14 (77.8)

2 (11.1)

16 (88.9)

IIIB

14 (23.7)

13 (92.9)

3 (21.4)

12 (85.7)

IV

4 (6.8)

4 (100)

1 (25.0)

2 (50.0)

  1. * The positive rate of P-gp is correlated positively with clinical stages (r = 0.742).