Relationship between the expression of hTERT and EYA4 mRNA in peripheral blood mononuclear cells with the progressive stages of carcinogenesis of the esophagus

Table 5 The sensitivity and specificity for the positive expression of hTERT and EYA4 mRNA combing the traditional risk factors by discrimination analysis

Model	Original group	Predicted group membership		sensitivity	Specificity
1	Discrimination of ESCC/control:	control	ESCC
	control	44	6	80.0%	88.0%
	ESSC	10	40
	Ungrouped cases	54	46
2	Discrimination of ESCD/control:	control	ESCC
	control	38	12	64.0%	76.0%
	ESCC	18	32
	Ungrouped cases	44	56
3	Discrimination of ESCD/control:	control	ESCD
	control	38	12	70.0%	76.0%
	ESCD	15	35
	Ungrouped cases	27	73
4	Discrimination of ESCD/control:	control	ESCD
	control	39	11	64.0%	76.0%
	ESCD	18	32
	Ungrouped cases	41	59

Note: The discrimination model 1 and model 3 included variables of the hTERT and EYA4 and the five traditional risk factors (sex, age, smoking, alcohol drinking and family history of esophageal cancer). The discrimination model 2 and model 4 only included the five traditional risk factors. ESCD, esophageal squamous cells dyspalsia; ESCC, esophageal squamous cells cancer.

ISSN: 1756-9966