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Table 1 Experimental lung metastasis in syngeneic mice after intravenous injection of B16 melanoma or F3II mammary carcinoma cells, preincubated or not with NeuGc-rich BSM.

From: Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines

Treatment Lung metastasisA
(nodules per animal)
  B16 cells F3II cells
Control 6.4 ± 2.2 6.2 ± 2.1
BSM-preincubated 11.6 ± 1.5* 13.3 ± 3.1*
  1. ALung nodules were counted 22 days after intravenous injection of B16 or F3II cells (1 × 105 cells/mouse). Values represent mean ± SEM of at least 10 mice.
  2. *p < 0.05 versus the respective control (Mann-Whitney U test).