Table 3 Univariate and multivariate analyses of prognostic factors
Independent factors | Univariate P | Multivariate P | Hazard ratio | 95% confidence interval |
|---|---|---|---|---|
pT | Â | Â | Â | Â |
   (pT1, 2/pT3, 4) | <.0001 | <.0001 | 2.767 | 1.734-4.526 |
pN | Â | Â | Â | Â |
   (pN0/pN1) | <.0001 | 0.1490 | 1.588 | 0.848-3.006 |
pM | Â | Â | Â | Â |
   (pM0/pM1) | <.0001 | 0.0042 | 2.013 | 1.247-3.278 |
Lymphatic invasion | Â | Â | Â | Â |
   (Negative/Positive) | 0.0001 | 0.6098 | 1.159 | 0.661-2.060 |
Venous invasion | Â | Â | Â | Â |
   (Negative/Positive) | 0.0057 | 0.6879 | 1.094 | 0.704-1.690 |
Twist | Â | Â | Â | Â |
   (Low/High) | 0.0021 | 0.6635 | 0.898 | 0.554-1.465 |
E-cadherin | Â | Â | Â | Â |
   (Preserved/Reduced) | 0.0007 | 0.0307 | 2.247 | 1.083-4.424 |
Combination of Twist and E-cadherin | Â | Â | Â | Â |
   (Twist low + E-cadherin preserved/other groups) | <.0001 | 0.0371 | 2.547 | 1.059-5.986 |