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Table 1 List of identified proteins differentially expressed between Eahy926 and A549 cells

From: Biological behaviors and proteomics analysis of hybrid cell line EAhy926 and its parent cell line A549

Spot ID

Swissa)

Gene name

Protein name

Function

Tb) PI

Tc) Mr

Scored)

Idie)

Exf) E/A

A1

P15121

AKR1B1

Aldose reductase (AR)

metabolism

6.56

36099

50

TMS

down

A2

P04179

SOD2

Superoxide dismutase [Mn]

metabolism

8.35

24878

38

TMS

down

A3

P11413

G6PD

Glucose-6-phosphate 1-dehydrogenase

metabolism

6.44

59553

276

PMF/TMS

down

A4

P29401

TKT

Transketolase (TK)

metabolism

7.58

68519

119

PMF/TMS

down

A5

P50395

GDI2

Rab GDP dissociation inhibitor beta

metabolism

6.11

51807

164

PMF/TMS

down

A6

P06748

NPM1

Nucleophosim (NPM)

metabolism

4.64

32726

116

PMF/TMS

down

A7

P43490

NAMPT

Nicotinamide phosphoribosyltransferase

metabolism

6.69

55772

57

TMS

down

A8

P31947

YWHAQ

14-3-3 protein sigma

differation/proliferation

4.68

27871

57

TMS

down

A9

P07355

ANXA2

Annexin A2 (Annexin?)

calcium ion binding

7.56

38677

347

PMF/TMS

down

A10

P10809

HSPD1

60 kDa heat shock protein

molecular chaperone

5.70

61187

370

PMF/TMS

down

A11

O75306

NDUFS2

NADH-ubiquinone oxidoreductase

metabolism

7.21

52911

37

TMS

down

A12

P60891

PRPS1

Ribose-phosphate pyrophosphokinase?

metabolism

6.56

35194

103

PMF/TMS

down

A13

P15559

NQO1

NAD(P)H dehydrogenase

metabolism

8.91

30905

38

TMS

down

E1

P05787

KRT8

Cytokeratin-8 (CK-8)

structural

5.52

53540

131

PMF/TMS

up

E2

P08238

HSP90AA1

Heat shock protein HSP 90

molecular chaperone

4.94

84875

58

TMS

up

E3

P07858

CTSB

Cathepsin B precursor (Cathepsin B)

migration/inv-asion

5.28

38766

84

TMS

up

E4

P62333

PSMC6

26s protease regulatory subunit

metabolism

7.10

44430

76

TMS

up

E5

P05783

KRT18

Cytokeratin-18 (CK18)

structural

5.34

47897

107

PMF/TMS

up

E6

P48643

CCT5

T-complex protein (TCP-1) (CCT)

molecular chaperone

5.45

60089

82

TMS

up

E7

P08670

VIM

Vimentin

structral

5.06

53545

38

TMS

up

E8

P68032

ACTC

Alpha-cardiac action

migration/inv-asion

5.23

42334

57

TMS

up

E9

P00491

NP

Purine nucleoside phosphorylase (PNP)

metabolism

6.45

32325

64

TMS

up

E10

P00338

LDHA

L-lactate dehydrogenase A (LDH-A)

metabolism

8.46

36819

41

TMS

up

E11

P22626

HNRPA2B1

hnRNP A2/B1

differation/proliferation

8.97

37464

173

PMF/TMS

up

E12

P11021

HSPA5

78 kDa glucose-regulated protein

molecular chaperone

5.07

72402

299

PMF/TMS

up

E13

P63244

GNB2L1

Guanine nucleotide-bingding protein

signal transduction

7.56

35380

199

PMF/TMS

up

E14

P31948

STIP1

Stress-induced-phosphoprotein 1

molecular chaperone

6.40

63227

30

TMS

up

E15

P26641

EEF1G

Elongation factor 1-gamma

structural

6.27

50298

113

PMF/TMS

up

  1. a) Swiss: SWISS-PROT accession number; b) T pI: theoretical isoelectric point of the matching protein; c) T Mr: theoretical relative molecular mass of the matching protein; d) Score: the score of PMF and TMS; e) Idi: identification method; TMS: tandem mass spectrometry; PMF: peptide mass fingerprinting; f) Ex E/A: expression level in Eahy926/A549 cells