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Table 1 List of identified proteins differentially expressed between Eahy926 and A549 cells

From: Biological behaviors and proteomics analysis of hybrid cell line EAhy926 and its parent cell line A549

Spot ID Swissa) Gene name Protein name Function Tb) PI Tc) Mr Scored) Idie) Exf) E/A
A1 P15121 AKR1B1 Aldose reductase (AR) metabolism 6.56 36099 50 TMS down
A2 P04179 SOD2 Superoxide dismutase [Mn] metabolism 8.35 24878 38 TMS down
A3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase metabolism 6.44 59553 276 PMF/TMS down
A4 P29401 TKT Transketolase (TK) metabolism 7.58 68519 119 PMF/TMS down
A5 P50395 GDI2 Rab GDP dissociation inhibitor beta metabolism 6.11 51807 164 PMF/TMS down
A6 P06748 NPM1 Nucleophosim (NPM) metabolism 4.64 32726 116 PMF/TMS down
A7 P43490 NAMPT Nicotinamide phosphoribosyltransferase metabolism 6.69 55772 57 TMS down
A8 P31947 YWHAQ 14-3-3 protein sigma differation/proliferation 4.68 27871 57 TMS down
A9 P07355 ANXA2 Annexin A2 (Annexin?) calcium ion binding 7.56 38677 347 PMF/TMS down
A10 P10809 HSPD1 60 kDa heat shock protein molecular chaperone 5.70 61187 370 PMF/TMS down
A11 O75306 NDUFS2 NADH-ubiquinone oxidoreductase metabolism 7.21 52911 37 TMS down
A12 P60891 PRPS1 Ribose-phosphate pyrophosphokinase? metabolism 6.56 35194 103 PMF/TMS down
A13 P15559 NQO1 NAD(P)H dehydrogenase metabolism 8.91 30905 38 TMS down
E1 P05787 KRT8 Cytokeratin-8 (CK-8) structural 5.52 53540 131 PMF/TMS up
E2 P08238 HSP90AA1 Heat shock protein HSP 90 molecular chaperone 4.94 84875 58 TMS up
E3 P07858 CTSB Cathepsin B precursor (Cathepsin B) migration/inv-asion 5.28 38766 84 TMS up
E4 P62333 PSMC6 26s protease regulatory subunit metabolism 7.10 44430 76 TMS up
E5 P05783 KRT18 Cytokeratin-18 (CK18) structural 5.34 47897 107 PMF/TMS up
E6 P48643 CCT5 T-complex protein (TCP-1) (CCT) molecular chaperone 5.45 60089 82 TMS up
E7 P08670 VIM Vimentin structral 5.06 53545 38 TMS up
E8 P68032 ACTC Alpha-cardiac action migration/inv-asion 5.23 42334 57 TMS up
E9 P00491 NP Purine nucleoside phosphorylase (PNP) metabolism 6.45 32325 64 TMS up
E10 P00338 LDHA L-lactate dehydrogenase A (LDH-A) metabolism 8.46 36819 41 TMS up
E11 P22626 HNRPA2B1 hnRNP A2/B1 differation/proliferation 8.97 37464 173 PMF/TMS up
E12 P11021 HSPA5 78 kDa glucose-regulated protein molecular chaperone 5.07 72402 299 PMF/TMS up
E13 P63244 GNB2L1 Guanine nucleotide-bingding protein signal transduction 7.56 35380 199 PMF/TMS up
E14 P31948 STIP1 Stress-induced-phosphoprotein 1 molecular chaperone 6.40 63227 30 TMS up
E15 P26641 EEF1G Elongation factor 1-gamma structural 6.27 50298 113 PMF/TMS up
  1. a) Swiss: SWISS-PROT accession number; b) T pI: theoretical isoelectric point of the matching protein; c) T Mr: theoretical relative molecular mass of the matching protein; d) Score: the score of PMF and TMS; e) Idi: identification method; TMS: tandem mass spectrometry; PMF: peptide mass fingerprinting; f) Ex E/A: expression level in Eahy926/A549 cells