Figure 7

RASSF1A promotes apoptosis that is enhanced by K-RasG12V. (a) CNE-2 cells were transiently transfected with empty vector and RASSF1A-expression vectors in the presence or absence of activated K-Ras, 48 h post transfection, empty vector cells showed 4.1% of apoptosis rate, RASSF1A expression cells was 22.7%, and RASSF1A + activated K-Ras expression CNE-2 cells showed 36.0% of apoptosis rate. (b) The statistical analysis of the apoptotic cells in each group. *: vs Vector group, p < 0.001; (Black triangle): vs RASSF1A group, p < 0.001.