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Table 4 Characteristics of the established cell lines regarding proliferation parameters, DNA content and gene expression.

From: Comparison of cisplatin sensitivity and the 18F fluoro-2-deoxy 2 glucose uptake with proliferation parameters and gene expression in squamous cell carcinoma cell lines of the head and neck

Cell line

Flowcytometry

(n = 1)

  

Immunohistochemistry

(n = 3)

PCR_SSCP

(n = 1)

FISH

(n = 1)

Cytogenetics

(n = 1)

LU-HNxSCC

Ploidity

DNA indices

S%phase

Cyclin D1

Tp53

Cyclin D1

 

3

Diploid (p4)

1

ND*

A

0

0

not complex

4

Nondilploid (p22)

1,4

26,3

C

exon7 R249G

0

complex

5

Nondiploid (p27)

2,1

23,8

D

exon5 H168P

++

complex

6

Nondiploid (p20)

1,2

16

A

0

0

complex

7

Nondiploid (p6)

1,4

9,8

A

0

deletion

complex

8

Nondiploid (p22)

1,6

22,2

B(1/3C)

exon7 Ldel252

1/3+

complex

  1. * ND = not determined