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Table 2 I.p. application of trAb anti-EpCAM and side effects

From: Induction of anti-tumor immunity by trifunctional antibodies in patients with peritoneal carcinomatosis

Pat. TrAb anti-EpCAM therapy (μg i.p./day) Cumulative dose Side effects
  μg day μg day μg day (μg)  
A 10 1 20 5 20 9 50 Elev. of AP (3), γ-GT (4); fever (3); abdominal pain (3); vomiting (3)
B 10 1 20 6 40 9 70 Elev. of AP (2), bilirubin (2), γ-GT (3), GOT (3), GPT (3); fever (3); abd. pain (3); vomiting (2); allergic exanthema (2)
C 5 1 20 3 40 7 65 Fever (2)
F 10 1 20 5 -   30 Elev. of AP (2), PTT (2), GPT (3); fever (1); abdominal pain (3); vomiting (2)
G 10 1 20 5 40 10 70 Elev. of AP (1), bilirubin (2), γ-GT (3), GPT (3); fever (1); abdominal pain (3)
H 10 1 20 7 40 13 70 Elev. of AP (1), bilirubin (2), gGT (3), creatinine (2); fever (1); abdominal pain (3)
I 10 1 20 8 40 12 70 Elev. of AP (1); fever (2); vomiting (3)