Table 2 I.p. application of trAb anti-EpCAM and side effects
Pat. | TrAb anti-EpCAM therapy (μg i.p./day) | Cumulative dose | Side effects | |||||
|---|---|---|---|---|---|---|---|---|
μg | day | μg | day | μg | day | (μg) | ||
A | 10 | 1 | 20 | 5 | 20 | 9 | 50 | Elev. of AP (3), γ-GT (4); fever (3); abdominal pain (3); vomiting (3) |
B | 10 | 1 | 20 | 6 | 40 | 9 | 70 | Elev. of AP (2), bilirubin (2), γ-GT (3), GOT (3), GPT (3); fever (3); abd. pain (3); vomiting (2); allergic exanthema (2) |
C | 5 | 1 | 20 | 3 | 40 | 7 | 65 | Fever (2) |
F | 10 | 1 | 20 | 5 | - | 30 | Elev. of AP (2), PTT (2), GPT (3); fever (1); abdominal pain (3); vomiting (2) | |
G | 10 | 1 | 20 | 5 | 40 | 10 | 70 | Elev. of AP (1), bilirubin (2), γ-GT (3), GPT (3); fever (1); abdominal pain (3) |
H | 10 | 1 | 20 | 7 | 40 | 13 | 70 | Elev. of AP (1), bilirubin (2), gGT (3), creatinine (2); fever (1); abdominal pain (3) |
I | 10 | 1 | 20 | 8 | 40 | 12 | 70 | Elev. of AP (1); fever (2); vomiting (3) |