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Table 4 Restimulation and response

From: Induction of anti-tumor immunity by trifunctional antibodies in patients with peritoneal carcinomatosis

Patient

Increase of IFN-γ secreting T-lymphocytes

HAMA (ng/ml)

Chemotherapy after trAb therapy

Survival after trAb therapy (months)

A

+

801

-

1

B

+

230

+

21

C

-

30512

+

31

D

-

n.d.

-

4

E

+

7870

+

7

F

-

50730

+

12

G

+

2540

+

15

H

-

400

+

8

I

+

n.d.

-

7

  1. Increase of IFN-γ secreting T-lymphocytes compared to baseline values before therapy. HAMA = human anti-mouse antibody reaction (values measured 4 weeks after trAb therapy).