Figure 2

To further observe and determine the inflammatory factors in the interaction between tumor and inflammation, results showed that: A.) the level of IFN-γ in the serum in the wound group continued a high level of expression (day 7 p < 0.01, day 11 p < 0.01); B.) in tumor tissue also detected high concentrations compared with the control group (day 7 p < 0.01, day 11 p < 0.01). Interestingly, at the 11th day, the tumor with the TGF-β increased, the result is that: C.) high levels of TGF-β can also be detected in the serum (day 7 p > 0.05, day 11 p < 0.01); D.) the same change in tumor (day 7 p > 0.05, day 11 p < 0.01). The TGF-β level before day 7 is not clear in terms of the present low of expression and secretion of tumor cells. That showed that at this time, the tumor does not have to go through the regulation of TGF-β to go against the ability of IFN-γ. When the IFN-γ-induces inhibition of tumor necrosis and persistence over a period, the role of TGF-β has been demonstrated, giving the tumor cells the ability to fight against the IFN-γ, so that the tumor cells could grow.