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Table 1 The correlation of survivin and HIF-1α expression with clinical pathology in NSCLC.

From: Effect of hypoxia-inducible factor-1α on transcription of survivin in non-small cell lung cancer

  

HIF-1α protein

 

Survivin protein

 

Clinical Pathology

N

positive

positive rate (%)

p

positive

positive rate (%)

p

sex

       

male

94

56

59.6

>0.05

79

84.0

>0.05

female

26

14

53.8

 

19

73.1

 

age

       

≤60

67

41

61.2

>0.05

52

77.6

>0.05

>60

53

29

54.7

 

46

86.8

 

degree of differentiation

       

high

45

19

42.2

<0.01

31

68.9

<0.01

moderate

46

29

63.0

 

39

84.8

 

low or undifferentiation

29

22

75.9

 

28

96.6

 

clinical stage

       

I~II

43

18

41.9

<0.01

29

72.1

<0.01

III

77

52

67.5

 

69

87.0

 

lymph nodes metastasis

       

yes

73

49

67.1

<0.01

66

90.4

<0.01

no

47

21

44.7

 

32

68.1

 

Survivin Positive**

98

63

90(63/70)

   

= 0.005

  1. Note: ** : rs = 0.255, p = 0.005.