Table 4 Distribution of GSTP1, GSTT1 and GSTM1 genotypes in controls and patients with prostate cancer.
Polymorphism | Controls Number (%) of subjects | Cases Number (%) of subjects | 95% CI for proportion difference | Cramér's V | OR (95% CI) | p-value |
|---|---|---|---|---|---|---|
GSTP1 | ||||||
No. | 228 | 129 | ||||
Ile/Ile | 110 (48.2) | 56 (43.4) | 1.0 | |||
Ile/Val+Val/Val | 118 (51.8) | 73 (56.6) | -0.15 to 0,06 | 0.047 | 0.72 (0.45 to 1.13) | 0.38 |
Val/Val | 5 (2.2) | 6 (4.7) | -0,08 to 0,01 | 0.068 | 2.17 (0.54 to 9.18) | 0.22 |
GSTT1 | ||||||
No. | 228 | 129 | ||||
positive | 183 (80.3) | 105 (81.4) | 1.0 | |||
null | 45 (19.7) | 24 (18.6) | -0.08 to 0.09 | -0.014 | 0.93 (0.51 to 1.66) | 0.80 |
GSTM1 | ||||||
No. | 228 | 129 | ||||
positive | 98 (43.0) | 60 (46.5) | 1.0 | |||
null | 130 (57.0) | 69 (53.5) | -0,07 to 0,14 | 0.034 | 0.87 (0.55 to 1.37) | 0.52 |