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Table 1 Main characteristics of MGUS, MM patients and healthy controls

From: Reduction of serum IGF-I levels in patients affected with Monoclonal Gammopathies of undetermined significance or Multiple Myeloma. Comparison with bFGF, VEGF and K-ras gene mutation

Group (n)

MGUS (71)

MM (77)

Control (55)

Gender

   

Male

38

49

28

Female

33

28

27

Age (y)

   
 

65.9 ± 10.5

66.7 ± 10.7

59.6 ± 14.5

Isotype (H)

   

IgG

62

48

--

IgA

3

28

--

IgM

6

--

--

IgD

--

1

--

Isotype (L)

   

K

38

54

--

λ

33

23

--

s-M Protein (g/L)

   
 

9.42 ± 4.61

25.8 ± 10.7

--

Bence Jones

   

Yes

41

63

--

No

30

14

--

Clinical stage (*)

   
 

--

I – II

--

  1. Age is given as mean ± SD. MGUS vs MM: p = 0.11; MGUS vs CTR: p = 0.005; MM vs CTR: p = 0.0001; Gender: MGUS vs MM: p = 0.30; MGUS vs CTR: p = 0.91; MM vs CTR: p = 0.21. s-M Protein concentration is expressed as mean ± SD. MGUS vs MM: p = 0.0001 (*) according to the Durie & Salmon criteria [26].