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Table 5 The genotype and allele frequency and odds ratios (OR) of the Arg194Trp polymorphism of XRCC1 gene in patients with head and neck cancer with different tumor size and lymph node status.

From: Genetic polymorphisms in DNA base excision repair gene XRCC1 and the risk of squamous cell carcinoma of the head and neck

  Tumour size (T) Node status (N)
Genotype Allele T3 + T4
Number/Frequency
T1+ T2
Number/Frequency
OR (95% CI) N1 + N2 + N3
Number/Frequency
N0
Number/Frequency
OR (95% CI)
Arg/Arg 43 (0.72) 28 (0.88) 0.36 (0.11 – 1.19) 20 (0.67) 51 (0.82) 0.43 (0.16 – 1.67)
Arg/Trp 17 (0.28) 4 (0.12) 2.76 (0.84 – 9.08) 10 (0.33) 11 (0.18) 2.32 (0.85 – 6.30)
Trp/Trp 0 (0.00) 0 (0.00) --------- 0 (0.00) 0 (0.00) ---------
Arg 103 (0.86) 60 (0.96) 0.40 (0.13 – 1.27) 50 (0.83) 113 (0.91) 0.48 (0.19 – 1.32)
Trp 17 (0.14) 4 (0.14) 2.47 (0.80 – 7.70) 10 (0.17) 11 (0.09) 2.05 (0.82 – 5.14)