High Erk-1 activation and Gadd45a expression as prognostic markers in high risk pediatric haemolymphoproliferative diseases

Table 4 Outcome of patients studied and proteins status

	GADD45a				pERK1				c-JUN				CASPASE 8
Score	0	1	2	p	0	1	2	p	0	1	2	p	0	1	2	p
ALL/NHL	12	12	3	0.004	3	10	14	0.8	10	10	7	0.9	6	10	11	0.8
Resistant/Relapse	12	0	0		3	6	9		10	8	7		6	7	9
AML	0	18	27	0.9	0	12	33	0.5	0	26	19		0	22	23
Resistant/Relapse	0	15	20		0	5	24		0	10	12	0.4	0	11	14	0.8

Score 0 = negative; 1 = 1–30% of positive cells; 2: > 30% of positive cells; p values in bold are statistically significant.

ISSN: 1756-9966