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Figure 4 | Journal of Experimental & Clinical Cancer Research

Figure 4

From: Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity

Figure 4

Effect of HPV-16 E5 expression on tyrosinase activity and pigment deposition and anchorage independent growth of amelanotic melanomas. Colony formation under anchorage independent culture conditions. The E5 expressing FRM cells displayed a moderated colony formation activity and a variable degree of pigment deposition while no colony nor pigmentation could ever been shown among control parental cells. Similar results were shown with M14 cells (data not shown). A representative experiment in a set of 3.

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