High
|
Further research is very unlikely to change our confidence in the estimate of effect
|
RCT or meta-analysis
|
Moderate
|
Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate
|
Downgraded RCTs or upgraded observational studies
|
Low
|
have an important impact on our confidence in the estimate of effect an its likely to change the estimate
|
Well-done observational studies with control groups
|
Very low
|
Any estimate of effect is very uncertain
|
Others (e.g., case reports or case series)
|