Table 2 Strength of recommendations and implication to quality of evidence.
Recommendation or statement | Description in GRADE approach | Interpretation |
|---|---|---|
Strong recommendation | We recommend (should) | 1. Most individuals should receive the intervention, assuming that they have been informed about and have understood its benefits, harms and burden. |
2. The recommendation could unequivocally be used for policy making. | ||
Weak recommendation | We suggest (might) | 1. Uncertainty about the relative importance of the benefits and downsides to those affected, or differences in how important they are to different people, which could affect the balance between the benefits versus harms and burden |
2. Doubt about the recommendation could be use for policy making |