Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

Table 1 Intra-individual Coefficients of Variance for TMA2 (CV%)^a

	Mean IOD	SD IOD	Mean CV%	SD CV%	SE CV%	n
1. eIF4E	62.7	26.2	26.4	24.5	7.8	10
2. c-Myc	68.1	23.3	28.1	16.1	4.9	11
3. Cyclin D1	51.2	32.5	55.9	45.1	14.2	10
4. ODC	55.2	23.4	30.7	27.2	8.6	10
5. TLK1B	38.9	26.3	46.9	38.5	11.6	11
6. VEGF	24.8	15.3	25.2	18.4	6.1	9
Overall			35.5	12.8	5.2	6

^aIntra-individual coefficient of variations (CV) was calculated as ratio. of standard deviation over mean × 100. The mean CV% and SD of CV for each marker was also added. The N's were added up in Table 1 as the number of replicate cases. Only those specimens in which 2–3 plugs could be analyzed are listed. So, in TMA2, there were up to 12 different cases, but only those that resulted in duplicate or triplicate plugs were analyzed for CV%. The overall mean and SD for integrated optical density (IOD) for each protein is also listed.

ISSN: 1756-9966