Figure 1

Single and combined effects of protons and FM on HTB140 cells. Viability (A), proliferation (B) and survival (C) of HTB140 cells estimated by SRB, BrdU and clonogenic assays, respectively, after single and combined treatments with protons and FM. Irradiation doses were 12 (I) and 16 Gy (II). Drug concentrations were 100 (III) and 250 μM (IV). (* – single or combined treatment vs. control, † – combined treatment vs. proton irradiation, # combined treatment vs. single drug treatment; 0.01 < p < 0.05 (*, †, #), 0.001 < p < 0.01 (**, ††, ##), p < 0.001 (***, †††, ###)).