indicates protein levels in HCT116 cells. The RhoA and RhoC proteins from cells infected with Ad-A1+A2+C1+C2 were significantly weaker than those from control cells or from cells infected with Ad-HK. GAPDH is used as a loading control (A). The graph (B) compares scanning signal intensity of RhoA and RhoC expression by Imagel software. *P > 0.05, no significantly difference between the cells treated with Ad-HK and the control cells. **P < 0.05, compared with other groups.