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Figure 5 | Journal of Experimental & Clinical Cancer Research

Figure 5

From: The effect of high frequency steep pulsed electric fields on in vitro and in vivo antitumor efficiency of ovarian cancer cell line skov3 and potential use in electrochemotherapy

Figure 5

Microphotos of SKOV3 cells under TEM observation. 5A: Abundant mitochondria and nucleoli with increased karyoplasm ratio in non-exposure cells. (TEM × 3500). 5B: In response to SPEF exposure (1 kHz), SKOV3 plasma membrane and karyotheca was disintegrated, subcellular organelles such as mitochondria, endoplasmic reticulum and nucleus were cavitated and swollen. (TEM × 3500). 5C: Typical characteristic of apoptosis was further induced by SPEF exposure (5 kHz). (TEM × 10000).

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