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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Alpha6beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer

Figure 1

Induced clustering of α6β4 (B) and EGFR (D, F). MDA-MB-231 cells were exposed to anti-β4 on ice, followed by control rabbit IgG (A, C, E) or rabbit anti-mouse IgG (B, D, F) at 37°C to crosslink α6β4 for 30 min (A, B), 5 min (C, D), or 15 min (E, F). Cells were stained with either FITC-labeled anti-mouse IgG to detect β4 (A, B) or FITC-labeled anti-EGFR (C-F).

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